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Cd163 Antibody - China

price: 299.00 Dollar US$

Cd163 Antibody

Products Photos Catalog Cd163 Antibody Photos Catalog

Product Name: CD163 Antibody

Code : CSB-RA801238A0HU

Abbreviation : Scavenger receptor cysteine-rich type 1 protein M130

Storage : Upon receipt, store at -20°C or -80°C.

Avoid repeated freeze.

Immunogen : A synthesized peptide

Species Reactivity : Human

Tested Applications : ELISA, IHC, FC; Recommended dilution: IHC: 1: 50-1: 500

Relevance : Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage.

May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme.

Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner.

Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype.

Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1 - Isoform 3 exhibits the higher capacity for ligand endocytosis and the more pronounced surface expression when expressed in cells.

After shedding, the soluble form (sCD163) may play an anti-inflammatory role, and may be a valuable diagnostic parameter for monitoring macrophage activation in inflammatory conditions.

Form : Liquid

Conjugate : Non-conjugated

Storage Buffer : Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification method : Affinity-chromatography

Isotype : Rabbit IgG

Clonality : Monoclonal

Alias : Scavenger receptor cysteine-rich type 1 protein M130, Hemoglobin scavenger receptor, CD163, Soluble CD163, sCD163, CD163, M130

Species : Human

Research Area : Immunology


Company Contact:


  • Phone: 862787582341

  • Address: Building B11, #818 Gaoxin Road, Wuhan , China

  • Email: Email


Published date: December 20, 2017

  • Business Description: CUSABIO is a leading biotechnology company specialized in production of

    high quality products for gene, protein, antibody, ELISA kit, raw

    material for production of diagnostic kit, drug residues, food safety

    small molecules & other small molecules.

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