Sell Recombinant Carboxypeptidase B Trypsin - China

RECOMBINANT CARBOXYPEPTIDASE B

RECOMBINANT TRYPSIN

FOR MANUFACTURING OF RECOMBINANT HUMAN INSULIN

Animal Origin Free, No Virus Contaminant

ANIMAL ORIGIN FREE

In the past 20 years, there has been a shift away from using bovine- or porcine-derived insulin to recombinant human insulin.

Recombinant human insulin is generally AOF level 1 component due to the usage of bovine- or porcine-derived trypsin and carboxypeptidase B in its manufacturing.

However, as worries about animal origin contaminants have increased, many biopharmaceutical companies have begun to consider producing AOF level 2 or AOF level 3 insulin.

YaxinBio offers recombinant trypsin and recombinant carboxypeptidase B as essential components for the AOF level 3 insulin production.

The value addition and safety offered in this AOF level 3 version provides a tremendous advantage to insulin manufacturers to fetch better market price in already crowded and pricesensitive insulin market-place.

USE OF RECOMBINANT CARBOXYPEPTIDASE B AND RECOMBINANT TRYPSIN IN INSULIN MANUFACTURING

Figure 1 - HPLC spectra of enzymatic digestion of human proinsuin.

Panel A and B correspond to enzymatic digestion of human proinsulin to generatehuman insulin with porcine-derived carboxypeptidase B and trypsin, and recombinant carboxypeptidase B and recombinant trypsin from YaxinBio, respectively.

PRODUCTS CHARACTERS

Source E.

Coli

Physical form lyophilized powder

Special activity ≥170 units/mg pro for recombinant carboxypeptidase B;

≥ 3000 USP units/ mg pro for recombinant trypsin.

Purified by HPLC

Purity ≥ 95%

Foreign activity No chymotrypsin, carboxypeptidase A, and other protease contaminant.



UNIT DEFINITION

One Unit of carboxypeptidase B activity hydrolyzes one micromole of hippuryl-L-arginine per

minute at 25℃, pH 7.65.

One USP unit of trypsin activity will produce a Delta A253 of 0.003 per minute in a reaction

volume of 3.0ml at pH7.6 at 25℃，with BAEE as a substrate (1cm light path).

PRODUCTS INFORMATION

Products Cat.

No Special Activity Manufacturer

Recombinant

Carboxypeptidase B RCPB01170 ≥170u/mg pro YaxinBio

Porcine Trypsin RPT03030 ≥3000 USP u/mg pro YaxinBio

Sell Recombinant Carboxypeptidase b Trypsin

Please inquiry for your need now

Company Contact:

• Posted By: China Shanghai Yaxin Biotechnology Co. Ltd

• Phone: 862154336592

• Address: Room 101, Building 1, No. 466 Yin Du Road, Xu Hui , shanghai , China

• Email:

• Website: https://www.yaxinbio.com

• Business Description: involved in international trade import export of goods, products, and services