Product Name Rat Protein Kinase B Pkb Akt Elisa Kit - China

Product Name: Rat Protein Kinase B (PKB/Akt) ELISA Kit

Product Type : ELISA Kit

Code : CSB-E12655r

Abbreviation : AKT1

Protein Biological Process 1 : Apoptosis/Autophagy

Alias : AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA, AKT1 kinase|RAC-alpha serine/threonine-protein kinase|protein kinase B|rac protein kinase alpha

Species : Rat

Protein Biological Process 3 : Apoptosis

Sample Types : serum, plasma, cell culture supernates, tissue homogenates

Research Area : Signal Transduction

Protocol :

Instructions

Protocol may be improved.

Please feel free to contact CUSABIO product specialist to obtain the latest version.

Target details : The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts.

AKT1 and the related AKT2 are activated by platelet-derived growth factor.

The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1 - It was shown that the activation occurs through phosphatidylinositol 3-kinase.

In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival.

Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery.

Multiple alternatively spliced transcript variants have been found for this gene.

Company Contact:

• Posted By: Cusabio Biotech Co., Ltd

• Phone: 862787582341

• Address: Building B11, #818 Gaoxin Road, Wuhan , China

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• Website: https://www.cusabio.com

• Business Description: CUSABIO is a leading biotechnology company specialized in production of
  
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  small molecules & other small molecules.