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Meltpro Mtb Inh Test Kit - China
price: 200.00 Dollar US$
MeltPro® Mycobacterium tuberculosis Isoniazid-resistance Mutation Test Kit
Mycobacterium tuberculosis Isoniazid-resistance Mutation Test is suitable for rapid, qualitative
detection of isoniazid-resistance mutations in Mycobacterium tuberculosis.
Mycobacterium tuberculosis Isoniazid-resistance Mutation Test is based on the Probe-based Melting
Curve Analysis.
According to the change in T m value between targets and the corresponding wild-type
probe sequences, the test detects the mutations in ahpC promoter region (positions -44~-30 and -15~3), inhA codon 94, inhA promoter region (positions -17~-8), and katG codon 315, which reports
isoniazid-resistance information.
Detection region: mutations in ahpC promoter region (positions -44~-30 and -15~3), inhA codon 94, inhA promoter region(positions -17~-8) and katG codon 315 (coverage rate: 50%-90% of all isoniazid-resistant mutants)
Principle of Probe-Based Melting Curve Analysis
Probe-based melting curve analysis is based on melting temperature generated by thermal denaturation of
the probe-target hybrid.
Melting curve plot of fluorescence (F) versus temperature (T) is transformed into
melting peak by plotting -dF/dT versus temperature.
The hybridization probe with fully matched wild-type
target gives the highest T m value.
With matched mutant-type target, it gives the lower T m value.
Mutation is detected as T m deviation (â–³T m ) compared to the wild-type hybrid.
Intended use: CFDA approved in China for clinical use, CE marked for IVD use in Europe.
Company Contact:
- Posted By: Zeesan Biotech
- Phone: 86-592-7615091
- Address: Building 1, 3701 Xiang'an North Road, Xiang'an District, Xiamen , Fujian , China
- Email:
- Website: http://www.zeesandx.com
Published date: July 12, 2017
- Business Description: Xiamen Zeesan Biotech Co., Ltd., is an ISO 13485: 2003-certified manufacturer specialized in providing an integrated solution for personalized medicine, including molecular diagnostic instruments, reagents, and consumable materials.
Our products are widely used in medical diagnosis for treatment of tuberculosis, leukemia, cervical cancer, and so on.
More than 30 products have got CFDA approval and 17 products are CE marked for clinical use in Europe.
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