Anti Gnaq Q209p Mouse Monoclonal Antibody - USA

Catalog Number: 26329

Gene Symbol: GNAQ, CMC1, G- ALPHA- q, GAQ, SWS

Description: Anti- GNAQ ( Q209P) Mouse Monoclonal Antibody

Background: GNAQ is a protein that in humans encoded by the GNAQ gene.

The GNAQ protein, an alpha subunit in the Gq class, couples a seven- transmembrane domain receptor to activation of phospholipase C- beta.

Mutations at this locus have been associated with problems in platelet activation and aggregation.

Immunogen: A synthetic peptide from the internal region of GNAQ which includes the mutation of Q209P, human origin.

Applications: ELISA, WB, IHC

Recommended Dilutions:

ELISA: 1: 1000- 1: 2000

WB: 1: 500- 1: 1000

IHC: 1: 50- 1: 100

Concentration: 1 mg/ ml

Host: Mouse

Format: Liquid

Clonality: Monoclonal

Isotype:

Purity: Purified from ascites

Storage buffer:

Preservative: no

Constituents: PBS ( without Mg2+ and Ca2+) , pH 7.4, 150 mM NaCl, 50% glycerol

Species Reactivity: Recognizes Q209P mutant, but not wild- type GNAQ of vertebrates.

Storage Conditions: Store at - 20°C.

Avoid freeze / thaw cycles

Company Contact:

• Posted By: NewEast Biosciences

• Phone: 6109452007

• Address: 24 Whitewoods Lane, Malvern , PA , USA

• Email:

• Website: http://www.neweastbio.com

• Business Description: NewEast Biosciences are specialized in generating protein configuration specific monoclonal antibodies that recognize active (GTP bound) G proteins (including Ras superfamily small GTPases and heterotrimeric G proteins).
  
  These unique antibodies do not recognize the inactive (GDP bound) G proteins.
  
  These monoclonal antibodies have been successfully used to immunoprecipitate active G proteins from cell lysates, and for immunohistochemical staining of active G proteins in cultured cells or in tissue sections.
  
  Hence, these antibodies can be used to study the spatial and temporal dynamics of cellular signaling involving big and small G proteins, the future direction of signal transduction studies.