Anti Pik3ca H1047r Rabbit Polyclonal Antibody - USA

Catalog Number: 21146

Gene Symbol: PIK3CA(H1047R)

Description: Anti-PIK3CA(H1047R) Rabbit Polyclonal Antibody

Background: Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit.

The catalytic subunit is encoded by the PIK3CA gene.

It phosphorylates PtdIns, PtdIns4P and PtdIns(4, 5)P2 - The PIK3CA gene is one of the most frequently mutated genes in human cancers.

Immunogen: A synthetic peptide around the H1047R region of PIK3CA, human origin.

Applications: ELISA, WB, IHC, IP

Recommended Dilutions:

ELISA: 1: 100-1: 5000

WB: 1: 100-1: 1000

IHC: 1: 10-1: 100

Concentration: 0.1 mg/ml

Host: Rabbit

Format: Liquid

Clonality: Polyclonal

Isotype:

Purity: Purified from serum

Storage buffer:

Preservative: no

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol

Species Reactivity: Anti-PIK3CA(H1047R) antibody recognizes PIK3CA(H1047R) of vertebrates.

Storage Conditions: Store at -20°C.

Avoid freeze / thaw cycles

Company Contact:

• Posted By: NewEast Biosciences

• Phone: 6109452007

• Address: 24 Whitewoods Lane, Malvern , PA , USA

• Email:

• Website: http://www.neweastbio.com

• Business Description: NewEast Biosciences are specialized in generating protein configuration specific monoclonal antibodies that recognize active (GTP bound) G proteins (including Ras superfamily small GTPases and heterotrimeric G proteins).
  
  These unique antibodies do not recognize the inactive (GDP bound) G proteins.
  
  These monoclonal antibodies have been successfully used to immunoprecipitate active G proteins from cell lysates, and for immunohistochemical staining of active G proteins in cultured cells or in tissue sections.
  
  Hence, these antibodies can be used to study the spatial and temporal dynamics of cellular signaling involving big and small G proteins, the future direction of signal transduction studies.